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Intraoperative Anaphylactic Reaction: Is it the Floseal?
Intraoperative Anaphylactic Reaction: Is it the Floseal?
- Source :
- The Journal of Pediatric Pharmacology and Therapeutics. 21:358-365
- Publication Year :
- 2016
- Publisher :
- Pediatric Pharmacy Advocacy Group, 2016.
-
Abstract
- When hemodynamic or respiratory instability occurs intraoperatively, the inciting event must be determined so that a therapeutic plan can be provided to ensure patient safety. Although generally uncommon, one cause of cardiorespiratory instability is anaphylactic reactions. During anesthetic care, these most commonly involve neuromuscular blocking agents, antibiotics, or latex. Floseal is a topical hemostatic agent that is frequently used during orthopedic surgical procedures to augment local coagulation function and limit intraoperative blood loss. As these products are derived from human thrombin, animal collagen, and animal gelatin, allergic phenomenon may occur following their administration. We present 2 pediatric patients undergoing posterior spinal fusion who developed intraoperative hemodynamic and respiratory instability following use of the topical hemostatic agent, Floseal. Previous reports of such reactions are reviewed, and the perioperative care of patients with intraoperative anaphylaxis is discussed.
- Subjects :
- Hemostatic Agent
medicine.medical_specialty
business.industry
medicine.medical_treatment
Orthopedic Surgical Procedure
Hemodynamics
Case Reports
medicine.disease
Neuromuscular Blocking Agents
Surgery
03 medical and health sciences
0302 clinical medicine
030202 anesthesiology
Spinal fusion
Anesthesia
Pediatrics, Perinatology and Child Health
Anesthetic
medicine
Pharmacology (medical)
business
030217 neurology & neurosurgery
Anaphylaxis
Adverse drug reaction
medicine.drug
Subjects
Details
- ISSN :
- 15516776
- Volume :
- 21
- Database :
- OpenAIRE
- Journal :
- The Journal of Pediatric Pharmacology and Therapeutics
- Accession number :
- edsair.doi.dedup.....05a5dd35be055a36445e3a171fd7d9da
- Full Text :
- https://doi.org/10.5863/1551-6776-21.4.358