Back to Search
Start Over
Non-target metabolomics revealed the differences between Rh. tanguticum plants growing under canopy and open habitats
- Source :
- BMC Plant Biology, Vol 21, Iss 1, Pp 1-13 (2021), BMC Plant Biology
- Publication Year :
- 2021
- Publisher :
- BMC, 2021.
-
Abstract
- Background Rheum tanguticum (Rh. tanguticum) is an important traditional Chinese medicine plant, “Dahuang”, which contains productive metabolites and occupies wide habitats on the Qinghai-Tibet plateau. Plants occupying wide habitats usually vary in phenotypes such as in morphology and metabolism, thereby developing into different ecotypes. Under canopy and open habitats are a pair of dissimilar habitats which possess Rh. tanguticum plants. However, few studies have focused on the effect of habitats on Rh. tanguticum growth, particularly combining morphological and metabolic changes. This study focused on Rh. tanguticum plants growing in under canopy and open habitats where morphology and metabolism changes were quantified using non-target metabolism methods. Results The obtained results indicated that the two dissimilar habitats led to Rh. tanguticum developing into two distinct ecotypes where the morphology and metabolism were simultaneously changed. Under canopy habitats bred morphologically smaller Rh. tanguticum plants which had a higher level of metabolites (22 out of 31) which included five flavonoids, four isoflavonoids, and three anthracenes. On the other hand, the open habitats produced morphologically larger Rh. tanguticum plants having a higher level of metabolites (9 out of 31) including four flavonoids. 6 of the 31 metabolites were predicted to have effect targets, include 4 represent for under canopy habitats and 2 for open habitats. Totally, 208 targets were connected, among which 42 were communal targets for both under canopy and open habitats represent compounds, and 100 and 66 were unique targets for under canopy superior compounds and open habitats superior compounds, respectively. In addition, aloe-emodin, emodin, chrysophanol, physcion, sennoside A and sennoside B were all more accumulated in under canopy habitats, and among which aloe-emodin, emodin, chrysophanol and physcion were significantly higher in under canopy habitats. Conclusions This study determined that Rh. tanguticum growing in under canopy and in open habitats developed into two distinct ecotypes with morphological and metabolic differences. Results of network pharmacology study has indicated that “Dahuang” coming from different habitats, such as under canopy and open habitats, are different in effect targets and thus may have different medicinal use. According to target metabolomics, under canopy habitats may grow better “Dahuang”.
- Subjects :
- 0106 biological sciences
0301 basic medicine
Canopy
Morphology
Ecotypes
Plant Science
Biology
01 natural sciences
03 medical and health sciences
Non target
Metabolomics
lcsh:Botany
Botany
Rheum
Ecosystem
Non-target metabolism
Plants, Medicinal
Ecotype
Agriculture
Sennoside B
Sennoside A
Habitats
lcsh:QK1-989
Rheum tanguticum
030104 developmental biology
Habitat
010606 plant biology & botany
Research Article
Drugs, Chinese Herbal
Subjects
Details
- Language :
- English
- ISSN :
- 14712229
- Volume :
- 21
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- BMC Plant Biology
- Accession number :
- edsair.doi.dedup.....058c96e126e8e599f8d4b6e4332748ef