Inadvertent hypothermia and acute kidney injury (AKI) in neonates undergoing gastrointestinal surgeries: a retrospective study

Objective The purpose of our study was to evaluate the association between intraoperative hypothermia and AKI in neonates undergoing gastrointestinal surgeries. Study design This retrospective study was conducted for neonates who underwent gastrointestinal surgeries from June 2018 to August 2020. Neonates with a minimum of two documented creatinine values before and after surgical procedures within 48 h were included. According to the mean intraoperative temperature, the eligible neonates were divided into three groups. The primary outcome was the incidence of AKI (as defined by the modified KDIGO criteria). The association between variables and AKI or hospital mortality was also examined. Results A total of 295 neonates fulfilled the eligibility criteria. AKI was more common in patients with lower intraoperative temperature compared to the normothermia group. Intraoperative mean temperature was independently associated with AKI. Patients developing AKI had a higher hospital mortality. AKI and gestational age were independently associated with hospital mortality. Conclusions Inadvertent intraoperative hypothermia was associated with developing postoperative AKI.