Additional file 4 of Oxidative stress gene expression, DNA methylation, and gut microbiota interaction trigger Crohn’s disease: a multi-omics Mendelian randomization study

Additional file 4: Fig. S2. Manhattan plots of colocalization between intestinal cis-eQTLs and mbQTLs. Six pairs of cis-eQTLs and mbQTLs with PPH4 > 0.5 were plotted for illustration: MUC1–CARNFORCAT.PWY, MUC1–PWWY.7237, CD40–PYRIDNUCSYN.PWY, CD40–PWY.5101, CD40–PWY.0845 and PRKAB1–P164.PWY. All microbial pathways were annotated by MetaCyc database ( https://metacyc.org/ ). The x-axis shows the chromosomal positions while the y-axis indicates the –log10 P values of SNPs.