Back to Search
Start Over
The amphibian testis as model to study germ cell progression during spermatogenesis
- Source :
- Comparative biochemistry and physiology. Part B, Biochemistrymolecular biology. 132(1)
- Publication Year :
- 2002
-
Abstract
- Testicular morphology of vertebrate testis indicates requirement of local control. In urodeles, the testis is organized in lobes of increasing maturity throughout the cephalocaudal axis. The anuran testis is organized in tubules. Spermatogenesis occurs in cysts composed by Sertoli cells enveloping germ cells at synchronous stages. Moreover, in numerous species germ cell progression lasts a year which defines the sexual cycle. Due to the above quoted features, research on factors regulating germ cell progression in amphibians may reach greater insight as compared with mammalian animal models. In particular, studies on endocrine and paracrine/autocrine factors involved in the regulation of germ cell functions reveal that fos activation and a J protein, previously specifically found in mouse testis, exert an important role in spermatogonial proliferation and maturation of post-meiotic stages, respectively.
- Subjects :
- Male
endocrine system
medicine.medical_specialty
Ranidae
Physiology
Blotting, Western
Biology
Biochemistry
Amphibians
Paracrine signalling
Mice
Meiosis
Internal medicine
Testis
medicine
Endocrine system
Animals
Autocrine signalling
Spermatogenesis
Molecular Biology
Sertoli Cells
Acrosome Reaction
Sertoli cell
Cell biology
medicine.anatomical_structure
Endocrinology
Germ Cells
Germ line development
Germ cell
Subjects
Details
- ISSN :
- 10964959
- Volume :
- 132
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Comparative biochemistry and physiology. Part B, Biochemistrymolecular biology
- Accession number :
- edsair.doi.dedup.....051dbfb63cab220964e87a95490086e7