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Brain activation patterns underlying upper limb bilateral motor coordination in unilateral cerebral palsy: an fNIRS study
- Source :
- Dev Med Child Neurol
- Publication Year :
- 2020
-
Abstract
- AIM To explore cortical activation during bimanual tasks and functional correlates in unilateral cerebral palsy (CP). METHOD This cross-sectional study included eight participants with unilateral CP (six females, two males; mean age [SD] 20y 10mo [5y 10mo], 13y 8mo-31y 6mo) in Manual Ability Classification System levels II to III and nine age-matched participants with typical development (seven females, two males; mean age [SD] 17y 8mo [5y 7mo], 9y 4mo-24y 2mo). They performed bimanual symmetric squeezing (BSS) and bimanual asymmetric squeezing (BAS) tasks at 1Hz, and a pouring task with dominant hand (DPour) and a pouring task with non-dominant hand (NDPour) at 0.67Hz, all while a custom array of functional near-infrared spectroscopy (fNIRS) optodes were placed over their sensorimotor area. Mixed-effects were used to contrast groups, tasks, and hemispheres (corrected p-values [q] reported). Analysis of variance and t-tests compared performance measures across groups and tasks. RESULTS Participants with unilateral CP showed greater activation in both hemispheres during BAS (non-lesioned: q
- Subjects :
- Adult
Male
Brain activation
medicine.medical_specialty
Manual Ability Classification System
Adolescent
Brain activity and meditation
Motor Activity
Audiology
Article
Cerebral palsy
Upper Extremity
Young Adult
03 medical and health sciences
0302 clinical medicine
Developmental Neuroscience
030225 pediatrics
medicine
Humans
Child
Spectroscopy, Near-Infrared
business.industry
Cerebral Palsy
Brain
Mean age
medicine.disease
Motor coordination
Cross-Sectional Studies
medicine.anatomical_structure
Pediatrics, Perinatology and Child Health
Upper limb
Female
Neurology (clinical)
Analysis of variance
Sensorimotor Cortex
business
030217 neurology & neurosurgery
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Dev Med Child Neurol
- Accession number :
- edsair.doi.dedup.....0514313f93940b195ba86dc38bc73635