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A double-blind randomized clinical evaluation of enamel matrix derivative proteins for the treatment of proximal class-II furcation involvements
- Source :
- Journal of Clinical Periodontology. 35:429-437
- Publication Year :
- 2008
- Publisher :
- Wiley, 2008.
-
Abstract
- Objective: The aim of the present randomized, double-blind study was to evaluate the clinical response of proximal furcations treated with enamel matrix derivative proteins (EMD). Material and Methods: Fifteen patients, each with a pair of contralateral class-II proximal furcation involvements, presenting probing depths (PDs) 5 mm and bleeding on probing (BOP) were selected. The patients were randomly assigned to: control group (n=15) – open flap debridement (OFD)+24% ethylenediaminetetraacetic acid (EDTA) conditioning; test group (n=15) – OFD+24% EDTA conditioning+EMD application. Plaque index (PI), BOP, PD, gingival margin position (GMP), relative vertical and horizontal clinical attachment level (RVCAL and RHCAL), vertical and horizontal bone level (VBL and HBL) and furcation closure were evaluated immediately before and 2, 4 and 6 months after the surgeries. Results: At 6 months, the RVCAL gains of the control and test group were 0.39 ± 1.00 and 0.54 ± 0.95 mm, while the RHCAL gains were 1.21 ± 2.28 and 1.36 ± 1.26 mm (p>0.05). The VBL and HBL gains of the control group were 1.04 ± 1.12 and 1.00 ± 1.79 mm, and 0.82 ± 1.82 and 1.17 ± 1.38 mm for the test group (p>0.05). In addition, a statistical difference was observed in the number of the remaining class-II furcations between the test and control groups (p
- Subjects :
- Male
Bleeding on probing
Dentistry
Statistics, Nonparametric
law.invention
Double blind
Dental Enamel Proteins
Double-Blind Method
Randomized controlled trial
law
Enamel matrix derivative
medicine
Humans
Edetic Acid
Chelating Agents
Analysis of Variance
business.industry
Furcation Defects
Open flap debridement
Middle Aged
Tooth enamel
Treatment Outcome
medicine.anatomical_structure
Periodontics
Female
Periodontal Index
medicine.symptom
business
Clinical evaluation
Gingival margin
Subjects
Details
- ISSN :
- 1600051X and 03036979
- Volume :
- 35
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Periodontology
- Accession number :
- edsair.doi.dedup.....04c3ddb51640142c08020ccfc6c3e2a1