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A Systematic Review of Exercise Interventions in Patients With Heart Failure
- Source :
- Biological Research For Nursing. 10:156-182
- Publication Year :
- 2008
- Publisher :
- SAGE Publications, 2008.
-
Abstract
- The incidence of heart failure (HF) is increasing as the population ages. Pharmacotherapy is an important component of treatment and yields significant improvements in survival and quality of life. In recent decades, exercise has gradually become accepted as an intervention beneficial to patients with HF, but more information is needed to clarify the effects of exercise and optimize interventions. Therefore, a systematic review of randomized controlled trials published from 1966 to October 2006 was carried out via PubMed. About 69 trials were reviewed, which used as main outcome measures: (a) central hemodynamic parameters, (b) peripheral blood flow, (c) endothelial function, (d) activation of neurohormones and cytokine systems, (e) structure of and metabolism in skeletal muscles, and/or (f) quality of life. Study findings suggest that the favorable physiological responses to exercise might slow some of the pathophysiological progression of HF. However, most of the trials reviewed here were based on relatively small samples and selected participant groups, and the exercise programs varied widely. These limitations and inconsistencies need to be addressed through further studies. Furthermore, reliable strategies for maintaining the positive effects of exercise and extending them to patients' daily life and quality of life are scarce in these trials. These domains need further exploration through rationally designed, large-scale randomized controlled trials.
- Subjects :
- Male
medicine.medical_specialty
Population
Psychological intervention
Hemodynamics
law.invention
Pharmacotherapy
Quality of life
Randomized controlled trial
law
medicine
Humans
Intensive care medicine
education
Exercise
Aged
Randomized Controlled Trials as Topic
Heart Failure
education.field_of_study
Research and Theory
business.industry
Incidence (epidemiology)
Middle Aged
medicine.disease
Heart failure
Physical therapy
Female
business
Subjects
Details
- ISSN :
- 15524175 and 10998004
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- Biological Research For Nursing
- Accession number :
- edsair.doi.dedup.....04a3f89da5d06274102d0ea2b3b8b1cd