Back to Search
Start Over
Cytotoxic sesquiterpenoids from soft soral capnella imbricata
- Source :
- Natural Product Communications. 14(6)
- Publication Year :
- 2019
- Publisher :
- SAGE Publications Inc, 2019.
-
Abstract
- A new sesquiterpene, capgermacrene H (1) was isolated together with 7 other compounds, capgermacrenes A-G (2-8), from a population of soft coral Capnella imbricata collected from Mantanani Island, Sabah, Malaysia. The structure of this metabolite was elucidated based on spectroscopic data such as nuclear magnetic resonance and high-resolution electrospray ionization mass spectrometry. Capgermacrene A (2) showed potent cytotoxicity against adult T-cell leukemia, S1T cells at half-maximal inhibitory concentration of 0.79 µg/mL.<br />論文
- Subjects :
- sesquiterpene
adult T-cell leukemia
Coral
Population
Plant Science
Biology
Capnella imbricata
Sesquiterpene
01 natural sciences
chemistry.chemical_compound
Drug Discovery
Botany
Capnella
education
Pharmacology
education.field_of_study
010405 organic chemistry
General Medicine
biology.organism_classification
capgermacrene H
0104 chemical sciences
010404 medicinal & biomolecular chemistry
Complementary and alternative medicine
chemistry
soft coral
cytotoxicity
Subjects
Details
- Language :
- Japanese
- ISSN :
- 1934578X
- Volume :
- 14
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Natural Product Communications
- Accession number :
- edsair.doi.dedup.....04621365bbe66228e2de446d02142e10