Comparison of Radiopaque Perfluorocarbon and Ethiodoi in Lymphography

Lymphangiography was performed on 40 adult cats, 39 dogs, 20 rabbits, and 12 rats of mixed sex using Ethiodoi® or radiopaque perfluorocarbon (RPC). Ethiodoi was more radio-dense than RPC, but imaging of lymph channels and nodes was satisfactory with the latter. RPC could be infused rapidly, while Ethiodoi infusion was time consuming. RPC was biologically inert; Ethiodoi produced both local and systemic inflammatory reactions. The lymph node distribution with RPC was more uniform and persisted for longer periods. It was concluded that RPC was an improvement over Ethiodoi for lymphangiography.