Total Synthesis of Polypropionate Natural Products: Application of New Sulfur Dioxide Chemistry

Authors :: Freddy Fonquerne
Pierre Vogel
Laure C. Bouchez
Xiaogen Huang
Māris Turks
Cotinica Craita
M. C. Murcia
Source :: Phosphorus, Sulfur, and Silicon and the Related Elements. 180:1223-1228
Publication Year :: 2005
Publisher :: Informa UK Limited, 2005.
Abstract: In the presence of a Lewis or protic acid at low temperature, electron-rich dienes add to sulfur dioxide and carbon nucleophiles generating silyl sulfinates. The latter can be transformed into valuable polyketide precursors.

Subjects :: Silylation
Organic Chemistry
Total synthesis
chemistry.chemical_element
General Medicine
Biochemistry
Inorganic Chemistry
chemistry.chemical_compound
Polyketide
chemistry
Nucleophile
Organic chemistry
Carbon
Sulfur dioxide

Tools