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Brain Malignancy Steering Committee clinical trials planning workshop: Report from the Targeted Therapies Working Group
- Source :
- Neuro-oncology, vol 17, iss 2
- Publication Year :
- 2014
- Publisher :
- Oxford University Press (OUP), 2014.
-
Abstract
- Glioblastoma is the most common primary brain malignancy and is associated with poor prognosis despite aggressive local and systemic therapy, which is related to a paucity of viable treatment options in both the newly diagnosed and recurrent settings. Even so, the rapidly increasing number of targeted therapies being evaluated in oncology clinical trials offers hope for the future. Given the broad range of possibilities for future trials, the Brain Malignancy Steering Committee convened a clinical trials planning meeting that was held at the Udvar-Hazy Center in Chantilly, Virginia, on September 19 and 20, 2013. This manuscript reports the deliberations leading up to the event from the Targeted Therapies Working Group and the results of the meeting.
- Subjects :
- Cancer Research
medicine.medical_specialty
Pathology
Poor prognosis
Endpoint Determination
Steering committee
Clinical Trials and Supportive Activities
Oncology and Carcinogenesis
Alternative medicine
Reviews
Malignancy
Systemic therapy
Rare Diseases
Clinical Research
medicine
Humans
Oncology & Carcinogenesis
Intensive care medicine
adaptive randomization
Cancer
clinical trials
Clinical Trials as Topic
Brain Neoplasms
business.industry
Surrogate endpoint
glioblastoma
Neurosciences
biomarkers
medicine.disease
Brain Disorders
Brain Cancer
Clinical trial
Orphan Drug
Oncology
Neurology (clinical)
Glioblastoma
business
Biomarkers
Subjects
Details
- ISSN :
- 15235866 and 15228517
- Volume :
- 17
- Database :
- OpenAIRE
- Journal :
- Neuro-Oncology
- Accession number :
- edsair.doi.dedup.....04136198c7bc5777459dd9012760975c