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Supplementary Figure 3 from Characterization of a New Class of Androgen Receptor Antagonists with Potential Therapeutic Application in Advanced Prostate Cancer

Authors :
Artem Cherkasov
Paul S. Rennie
Emma Tomlinson Guns
Helge Prinz
Konrad J. Böhm
Hans Adomat
Kriti Singh
Kate Frewin
Natalia Kanaan
Peyman Tavassoli
Eric Leblanc
Peter Axerio-Cilies
Nathan A. Lack
Mohamed D.H. Hassona
Huifang Li
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

PDF file, 162K, AR mRNA levels are unaffected upon treatment with VPC-3022 and VPC-3033. Total RNA was extracted after treatment of LNCaP and MDV3100-resistant cells with VPC-3022 and VPC-3033 for 24 hours at the indicated concentrations in the presence of 0.1 nM R1881. Quantitative RT-PCR analysis of AR expression was performed and normalized to 18S rRNA levels. Error bars indicate standard deviation.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....0406c04cd1febb6f269dbf52c712dfe4
Full Text :
https://doi.org/10.1158/1535-7163.22499370.v1