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Usefulness of Combined White Blood Cell Count and Plasma Glucose for Predicting In-Hospital Outcomes After Acute Myocardial Infarction
- Source :
- The American Journal of Cardiology. 97:1558-1563
- Publication Year :
- 2006
- Publisher :
- Elsevier BV, 2006.
-
Abstract
- Admission white blood cell (WBC) count and plasma glucose (PG) have been associated with adverse outcomes after acute myocardial infarction (AMI). This study investigated the joint effect of WBC count and PG on predicting in-hospital outcomes in patients with AMI. WBC count and PG were measured at the time of hospital admission in 3,665 patients with AMI. Patients were stratified into tertiles (low, medium, and high) based on WBC count and PG. Patients with a high WBC count had a 2.0-fold increase in in-hospital mortality compared with those with a low WBC count. Patients with a high PG level had a 2.7-fold increase in mortality compared with those with a low PG level. When a combination of different strata for each variable was analyzed, a stepwise increase in mortality was seen. There was a considerable number of patients with a high WBC count and low PG level or with a low WBC count and high PG level. These patients had an intermediate risk, whereas those with a high WBC count and high PG level had the highest risk, i.e., 4.8-fold increase in mortality, compared with those with a low WBC count and low PG level. Multivariate analysis was performed to assess the predictor for in-hospital mortality using WBC count and PG level as continuous variables and showed that WBC count and PG level were independently associated with in-hospital mortality. These findings suggested that a simple combination of WBC count and PG level might provide further information for predicting outcomes in patients with AMI.
- Subjects :
- Blood Glucose
Male
medicine.medical_specialty
Multivariate analysis
Heart disease
Myocardial Infarction
Gastroenterology
Continuous variable
Japan
Predictive Value of Tests
Risk Factors
hemic and lymphatic diseases
Internal medicine
White blood cell
medicine
Humans
Hospital Mortality
Myocardial infarction
Aged
Retrospective Studies
Inpatients
Plasma glucose
business.industry
Wbc count
Middle Aged
Prognosis
medicine.disease
Blood Cell Count
Surgery
medicine.anatomical_structure
Hospital outcomes
Cardiology
Female
Cardiology and Cardiovascular Medicine
business
Biomarkers
circulatory and respiratory physiology
Subjects
Details
- ISSN :
- 00029149
- Volume :
- 97
- Database :
- OpenAIRE
- Journal :
- The American Journal of Cardiology
- Accession number :
- edsair.doi.dedup.....0403ed526efbc7b4c12b24165142b698