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Conduct disorder, antisocial personality disorder and substance use disorders in schizophrenia and major affective disorders
- Source :
- Journal of Studies on Alcohol. 60:278-284
- Publication Year :
- 1999
- Publisher :
- Alcohol Research Documentation, Inc., 1999.
-
Abstract
- To examine the relationships between childhood conduct disorder (CD), antisocial personality disorder (ASPD) and substance use disorders (substance abuse or substance dependence) in psychiatric patients with severe mental illness.Substance use-related problems on screening instruments, lifetime and recent prevalence of substance use disorders, and family history of substance use disorder were evaluated in four groups of 293 patients with mainly schizophrenia-spectrum and major affective disorders: No ASPD/CD, CD Only, Adult ASPD Only, Full ASPD.Full ASPD was strongly related to all measures of substance use problems and disorders, as well as fathers' history of substance use disorder. The odds ratios for Full ASPD and substance use disorders ranged between 3.96 (lifetime cannabis use disorder) to 11.35 (recent cocaine use disorder). To a lesser extent, patients with CD Only or Adult ASPD Only were also at increased risk for having substance use disorders compared to the No ASPD/CD patients.Childhood CD and adult ASPD represent significant risk factors for substance use disorders in patients with schizophrenia-spectrum and major affective disorders. Considering other research indicating that CD and ASPD have a higher prevalence in patients with severe mental illness, the present findings suggest that CD and ASPD could reflect a common factor that independently increases patients' vulnerability to both psychiatric and substance use disorders.
- Subjects :
- Adult
Conduct Disorder
Male
medicine.medical_specialty
Substance-Related Disorders
Medicine (miscellaneous)
Poison control
Comorbidity
Risk Factors
mental disorders
Odds Ratio
Prevalence
medicine
Humans
New Hampshire
Child
Psychiatry
General Psychology
Retrospective Studies
Family Health
Chi-Square Distribution
Substance dependence
Mood Disorders
Antisocial personality disorder
Antisocial Personality Disorder
medicine.disease
Mental illness
Substance abuse
Cross-Sectional Studies
Diagnosis, Dual (Psychiatry)
Conduct disorder
Schizophrenia
Multivariate Analysis
Female
Psychology
Clinical psychology
Subjects
Details
- ISSN :
- 19342683 and 0096882X
- Volume :
- 60
- Database :
- OpenAIRE
- Journal :
- Journal of Studies on Alcohol
- Accession number :
- edsair.doi.dedup.....03f7298b302ff7a1789c8390a5daeb7d
- Full Text :
- https://doi.org/10.15288/jsa.1999.60.278