Field Evaluation of a Rota- and Adenovirus Immunochromatographic Assay Using Stool Samples from Children with Acute Diarrhea in Ghana

Authors :: Ulrich Bienzle
Thomas Weitzel
Eiman Saad
Eckart Schreier
Ralf Ignatius
Klaus Stark
Klaus Reither
Andrew Seidu-Korkor
Frank P. Mockenhaupt
Source :: Journal of Clinical Microbiology. 45:2695-2697
Publication Year :: 2007
Publisher :: American Society for Microbiology, 2007.
Abstract: We evaluated the Rida Quick rotavirus/adenovirus Combi rapid immunochromatographic test (ICT) under field conditions with Ghanaian children with acute diarrhea. Compared to PCR results, sensitivities and specificities were 75% and 95% for rotavirus and 22% and 84% for adenovirus. In resource-poor settings, ICTs may help to overcome difficulties in the diagnosis of rotavirus infection.

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