Back to Search
Start Over
Tabebuia impetiginosa: A Comprehensive Review on Traditional Uses, Phytochemistry, and Immunopharmacological Properties
- Source :
- Molecules, Vol 25, Iss 4294, p 4294 (2020), Molecules
- Publication Year :
- 2020
- Publisher :
- MDPI AG, 2020.
-
Abstract
- Tabebuia impetiginosa, a plant native to the Amazon rainforest and other parts of Latin America, is traditionally used for treating fever, malaria, bacterial and fungal infections, and skin diseases. Additionally, several categories of phytochemicals and extracts isolated from T. impetiginosa have been studied via various models and displayed pharmacological activities. This review aims to uncover and summarize the research concerning T. impetiginosa, particularly its traditional uses, phytochemistry, and immunopharmacological activity, as well as to provide guidance for future research. A comprehensive search of the published literature was conducted to locate original publications pertaining to T. impetiginosa up to June 2020. The main inquiry used the following keywords in various combinations in titles and abstracts: T. impetiginosa, Taheebo, traditional uses, phytochemistry, immunopharmacological, anti-inflammatory activity. Immunopharmacological activity described in this paper includes its anti-inflammatory, anti-allergic, anti-autoimmune, and anti-cancer properties. Particularly, T. impetiginosa has a strong effect on anti-inflammatory activity. This paper also describes the target pathway underlying how T. impetiginosa inhibits the inflammatory response. The need for further investigation to identify other pharmacological activities as well as the exact target proteins of T. impetiginosa was also highlighted. T. impetiginosa may provide a new strategy for prevention and treatment of many immunological disorders that foster extensive research to identify potential anti-inflammatory and immunomodulatory compounds and fractions as well as to explore the underlying mechanisms of this herb. Further scientific evidence is required for clinical trials on its immunopharmacological effects and safety.
- Subjects :
- Phytochemistry
Inflammatory response
Tabebuia impetiginosa
traditional uses
Pharmaceutical Science
Review
Biology
Analytical Chemistry
lcsh:QD241-441
03 medical and health sciences
0302 clinical medicine
lcsh:Organic chemistry
Drug Discovery
immunopharmacology
Physical and Theoretical Chemistry
030304 developmental biology
0303 health sciences
Traditional medicine
Organic Chemistry
immunological disorders
Immunopharmacology
Taheebo
Chemistry (miscellaneous)
030220 oncology & carcinogenesis
Molecular Medicine
Subjects
Details
- Language :
- English
- ISSN :
- 14203049
- Volume :
- 25
- Issue :
- 4294
- Database :
- OpenAIRE
- Journal :
- Molecules
- Accession number :
- edsair.doi.dedup.....03d4ca0dcad4aa68c29254a06f742599