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Invasive Candidiasis in Severe Acute Pancreatitis: Experience from a Tertiary Care Teaching Hospital
- Source :
- Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine
- Publication Year :
- 2017
-
Abstract
- Background: Invasive candidiasis (IC) is associated with increased morbidity in severe acute pancreatitis (SAP). There is limited information regarding the predisposing factors, Candida species distribution and in vitro susceptibility. Methodology: Current data have been derived from a larger prospective nonintervention study conducted on 200 critically ill patients which was done to study the antifungal prescription practices, collect epidemiological data, and perform an external validation of risk prediction models for IC under senior research associateship program of Council of Scientific and Industrial Research New Delhi. Of these critically ill patients, thirty had SAP and were included for analysis. Results: There were 23 males and 7 females. Out of eight patients (27%) who developed IC, three had isolated candidemia, two had isolated deep-seated candidiasis while three had both candidemia and deep-seated candidiasis. SAP patients with IC had a longer duration of Intensive Care Unit stay, hospital stay, days on mechanical ventilation and duration of shock. Mortality was not different between SAP patients with or without IC. Conclusion: There is a high rate of Candida infection in SAP. More studies are needed to generate epidemiological data and develop antifungal stewardship in this subset of high-risk population.
- Subjects :
- medicine.medical_specialty
medicine.medical_treatment
Population
Critical Care and Intensive Care Medicine
Brief Communication
Tertiary care
law.invention
03 medical and health sciences
0302 clinical medicine
law
Internal medicine
Epidemiology
medicine
Medical prescription
education
Intensive care medicine
Mechanical ventilation
education.field_of_study
business.industry
Candidemia
030208 emergency & critical care medicine
Invasive candidiasis
invasive candidiasis
medicine.disease
Intensive care unit
Acute pancreatitis
030211 gastroenterology & hepatology
business
severe acute pancreatitis
Subjects
Details
- ISSN :
- 09725229
- Volume :
- 21
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine
- Accession number :
- edsair.doi.dedup.....03d4bca1e7aab843d9a809bf038cca00