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Decreasing incidence and severity of Behçet’s disease: a changing trend in epidemiological spectrum possibly associated with oral health
- Source :
- Turkish Journal of Medical Sciences
- Publication Year :
- 2020
- Publisher :
- The Scientific and Technological Research Council of Turkey (TUBITAK-ULAKBIM) - DIGITAL COMMONS JOURNALS, 2020.
-
Abstract
- Behçet’s disease (BD) is a systemic and inflammatory disorder that is mainly present along the ancient Silk Road, from the Mediterranean Sea to East Asia. A wide range of prevalence figures (0.1–420/100,000) have been reported for BD, also among Turkish populations of similar genetic background living in different countries. Recently, a decline in the incidence of BD and a change of the disease spectrum to less-severe manifestations have been reported from Japan and Korea, two genetically homogenous, affluent populations with limited immigration. It was hypothesized that a decline in infectious diseases, especially dental/periodontal infections, associated with the improvement in oral health, could be a part of these changes in the disease expression. Further epidemiological studies in other populations might demonstrate whether there is a worldwide similar trend and may provide a better understanding of the triggering factors for the onset and course of BD.
- Subjects :
- Male
medicine.medical_specialty
Turkey
Disease
Behcet's disease
030204 cardiovascular system & hematology
Oral health
Article
Behçet’s disease
03 medical and health sciences
0302 clinical medicine
Japan
Republic of Korea
Epidemiology
medicine
Humans
East Asia
0303 health sciences
030306 microbiology
business.industry
Behcet Syndrome
Incidence
Incidence (epidemiology)
Disease spectrum
General Medicine
medicine.disease
Changing trend
oral health
Female
epidemiology
business
Demography
Subjects
Details
- ISSN :
- 13036165
- Volume :
- 50
- Database :
- OpenAIRE
- Journal :
- TURKISH JOURNAL OF MEDICAL SCIENCES
- Accession number :
- edsair.doi.dedup.....03aca96424e05a21ef04361c8858c179