Back to Search
Start Over
The carcinoembryonic antigen ratio is a potential predictor of survival in recurrent colorectal cancer
- Source :
- International Journal of Clinical Oncology. 26:1264-1271
- Publication Year :
- 2021
- Publisher :
- Springer Science and Business Media LLC, 2021.
-
Abstract
- The carcinoembryonic antigen (CEA) “value” itself is often useless in patients with a normal CEA level at initial presentation and those with tumor-irrelevant elevated CEA. Although the unified marker using CEA has been desirable for recurrent tumor staging as well as for primary tumor staging, little is known concerning its relationship with the survival of patients with recurrent colorectal cancer in particular. This retrospective historical study included patients who experienced disease relapse after curative surgery for stage I–III colorectal cancer between 2006 and 2018. A total of 129 patients with recurrent disease after curative surgery for colorectal cancer were included. We focused on the CEA “ratio” (CEA-R: the ratio of the CEA level at the time of recurrence to that measured 3 months before recurrence) and aimed to evaluate the correlation between CEA-R and survival in recurrent colorectal cancer. Patients with a high CEA-R (≥ 2) exhibited significantly worse 2 year survival than those with a low CEA-R (
- Subjects :
- 0301 basic medicine
Oncology
medicine.medical_specialty
Multivariate analysis
endocrine system diseases
Colorectal cancer
03 medical and health sciences
0302 clinical medicine
Carcinoembryonic antigen
Surgical oncology
Internal medicine
Humans
Medicine
Recurrent Colorectal Cancer
Stage (cooking)
neoplasms
Neoplasm Staging
Retrospective Studies
biology
business.industry
Primary resection
Hematology
General Medicine
Prognosis
medicine.disease
Primary tumor
digestive system diseases
Carcinoembryonic Antigen
030104 developmental biology
030220 oncology & carcinogenesis
biology.protein
Surgery
Neoplasm Recurrence, Local
Colorectal Neoplasms
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 14377772 and 13419625
- Volume :
- 26
- Database :
- OpenAIRE
- Journal :
- International Journal of Clinical Oncology
- Accession number :
- edsair.doi.dedup.....03738765bd818f099b4f877b9bba3cf9