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Enterobius vermicularis-associated appendicitis: A 22-year case series and comprehensive review of the literature
- Source :
- Journal of Pediatric Surgery. 57:1494-1498
- Publication Year :
- 2022
- Publisher :
- Elsevier BV, 2022.
-
Abstract
- Introduction Enterobius vermicularis is known to be associated with appendicitis, however a causal relationship between Enterobius and appendicitis has not been established. The aim of this study was to explore the relationship between appendiceal Enterobius and histologic appendicitis. Methods A retrospective review was performed of all pediatric appendectomies between 1997 and 2019. Patients with diagnosed with Enterobius were included for analysis. Patient demographics, operative findings, and pathologic reports were queried. Data were entered into an encrypted database and subsequently analyzed. A comprehensive review of the literature was also conducted. Results Thirty-eight cases of Enterobius-associated appendicitis were identified out of 3541 (1.07%). Grossly normal appendices at operation were seen in 27% of patients. Inflammatory infiltrate was noted on histopathology in 78.3%, and Enterobius was considered to be the cause of that inflammation in 68.4%. The comprehensive literature review revealed 19 articles (1.87% incidence) that noted 35% of patients with appendiceal Enterobius had appendicitis on either histopathology or gross evaluation. Conclusion The high rate of inflammation on pathology found among our patients with pinworm appendicitis suggests an association with presentation as acute appendicitis. Our comprehensive review revealed a higher proportion of Enterobius appendicitis. Treatment with antihelminthic therapy is recommended. Level of evidence (LOE) Level IV(4)-case series and comprehensive review.
- Subjects :
- medicine.medical_specialty
Patient demographics
Appendix
parasitic diseases
medicine
Animals
Appendectomy
Humans
Enterobius
Child
Inflammation
High rate
business.industry
Incidence (epidemiology)
General surgery
Enterobiasis
Level iv
General Medicine
Appendicitis
medicine.disease
Pediatrics, Perinatology and Child Health
Acute appendicitis
Surgery
Histopathology
business
Subjects
Details
- ISSN :
- 00223468
- Volume :
- 57
- Database :
- OpenAIRE
- Journal :
- Journal of Pediatric Surgery
- Accession number :
- edsair.doi.dedup.....033a76acb4125e4c456e4ffb525b50f9