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Orphan G protein receptor GPR55 as an emerging target in cancer therapy and management
- Source :
- Cancer Management and Research
- Publication Year :
- 2013
-
Abstract
- G protein-coupled receptors (GPCRs) modulate a vast array of cellular processes. The current review gives an overview of the general characteristics of GPCRs and their role in physiological conditions. In addition, it describes the current knowledge of the physiological and pathophysiological functions of GPR55, an orphan GPCR, and how it can be exploited as a therapeutic target to combat various cancers.
- Subjects :
- 0303 health sciences
business.industry
Cancer therapy
Computational biology
Review
Bioinformatics
Endocannabinoid system
3. Good health
03 medical and health sciences
0302 clinical medicine
GPCR
Oncology
GPR55
030220 oncology & carcinogenesis
Medicine
cancer
endocannabinoids
business
Receptor
hormones, hormone substitutes, and hormone antagonists
030304 developmental biology
G protein-coupled receptor
Subjects
Details
- ISSN :
- 11791322
- Volume :
- 5
- Database :
- OpenAIRE
- Journal :
- Cancer management and research
- Accession number :
- edsair.doi.dedup.....03344bdf5f18ada8ab2ca8949c4a391f