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Supplementary Tables 1-7, 9 from Genotype-Selective Combination Therapies for Melanoma Identified by High-Throughput Drug Screening

Authors :
David F. Stern
Marcus W. Bosenberg
Jonathan W. Haskins
Andrew Koo
Antonella Bacchiocchi
Ashok Chakraborty
Zongzhi Liu
Tisheeka Graham-Steed
James T. Platt
Casey G. Langdon
Matthew A. Held
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

PDF file - 169K, Table S1. Agents used in single-agent HTS; Table S2. Melanoma cell lines and mutation status; Table S3. Concentrations required to inhibit 50% of cell growth (GI50) in single-agent screens; Table S4. Single agents with significant genotype-selective efficacy; Table S5. Agents and concentrations chosen for cHTS; Table S6. Partial list of drug pairs showing genotype selectivity; Table S7. Genotype-selective combinations with simvastatin; Table S9. Combination index (CI) values for select drug combinations

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....03286a779e58d03b54f8600592317389