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[Analysis and evaluation of alkaloids and flavonoids in flower of Sophora flavescens from Shanxi province]
- Source :
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 41(24)
- Publication Year :
- 2016
-
Abstract
- This study intends to explore the potential resource-orientedutilization value of the flower of Sophora flavescents by analyzing alkaloids and flavonoids in the flower of S. flavescens from Shanxi province. This study established a rapid UPLC-TQ-MS/MS method that is used for determination of seven alkaloids and seven flavonoids in the flower of S.flavescens. The different florescences all have the seven detected alkaloids such as cytisine, oxy-matrine, oxy-sophocarpine, sophoridine, N-methylcytisine, matrine, sophocarpine.The total contents of detected alkaloids are as follows: flower buds 1.47%, primal flowers 1.34%, full bloomed flowers 1.17%, faded flowers 1.01%. The top three contents of alkaloids are N-methylcytisine , oxy-sophocarpine and oxymatrine, accounting for about 83% of the total amount of detected alkaloids. All the samples in different florescences have the seven detected flavonoids such as rutin, luteolin, quercetin, isoquercitrin, trifolirhizin, kurarinone, and kushenol I. The total contents of detected alkaloids are as follows: flower buds 495.2 μg•g⁻¹, primal flowers 313.7 μg•g⁻¹, faded flowers 224.2 μg•g⁻¹, full bloomed flowers 193.0 μg•g⁻¹. The content of luteolinis relatively higher than other detected flavonoids, accounting for about 89%-94% of the total amount of detected flavonoids. The results indicated that the flower of S.flavescens could be an important material resource to obtain the resourceful alkaloids. This result can provide scientific basis for resource-oriented utilization and industrial development of the flower of S. flavescens.
- Subjects :
- Flavonoids
China
Sophora
Sophora flavescens
Traditional medicine
Trifolirhizin
Phytochemicals
Flowers
Biology
biology.organism_classification
chemistry.chemical_compound
Rutin
Oxymatrine
Alkaloids
Complementary and alternative medicine
Matrine
chemistry
Tandem Mass Spectrometry
Pharmacology (medical)
General Pharmacology, Toxicology and Pharmaceutics
Quercetin
Luteolin
Chromatography, High Pressure Liquid
Quinolizines
Subjects
Details
- ISSN :
- 10015302
- Volume :
- 41
- Issue :
- 24
- Database :
- OpenAIRE
- Journal :
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Accession number :
- edsair.doi.dedup.....02f32dc9aee1c0b64b597acac379d8b7