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Changes in urinary potassium excretion in patients with chronic kidney disease
- Source :
- Kidney Research and Clinical Practice, Vol 35, Iss 2, Pp 78-83 (2016), Kidney Research and Clinical Practice
- Publication Year :
- 2016
- Publisher :
- Elsevier BV, 2016.
-
Abstract
- Background: Hyperkalemia is one of the more serious complications of chronic kidney disease (CKD), and the cause of potassium retention is a reduction in urinary potassium excretion. However, few studies have examined the extent of the decrease of urinary potassium excretion in detail with respect to decreased renal function. Methods: Nine hundred eighty-nine patients with CKD (CKD stages G1 and G2 combined: 135; G3a: 107; G3b: 170; G4: 289; and G5: 288) were evaluated retrospectively. Values for urinary potassium excretion were compared between CKD stages, and the associations between urinary potassium excretion and clinical parameters, including diabetes mellitus status and use of renin–angiotensin–aldosterone system inhibitors, were analyzed using a multivariable linear regression analysis. Results: Urinary potassium excretion gradually decreased with worsening of CKD (G5: 24.8 ± 0.8 mEq/d, P
- Subjects :
- lcsh:Internal medicine
medicine.medical_specialty
Urinary potassium
lcsh:Specialties of internal medicine
Hyperkalemia
Urology
030232 urology & nephrology
Renal function
030204 cardiovascular system & hematology
urologic and male genital diseases
POTASSIUM RETENTION
Excretion
03 medical and health sciences
0302 clinical medicine
lcsh:RC581-951
Chronic kidney disease
Medicine
In patient
Estimated glomerular filtration rate
lcsh:RC31-1245
Urinary potassium excretion
business.industry
medicine.disease
female genital diseases and pregnancy complications
Decreased renal function
Nephrology
Original Article
medicine.symptom
business
Kidney disease
Subjects
Details
- ISSN :
- 22119132
- Volume :
- 35
- Database :
- OpenAIRE
- Journal :
- Kidney Research and Clinical Practice
- Accession number :
- edsair.doi.dedup.....02e2152ee3d01ca267b3a8586b9197ce