IgG4-related airway involvement which developed in a patient receiving corticosteroid therapy for autoimmune pancreatitis

Authors :: Shigeyuki Kawa
Satoshi Kawakami
Akihiko Yoshizawa
Hiroshi Yamamoto
Yayoi Nomura
Hideaki Hamano
Keishi Kubo
Atsuhito Ushiki
Toshihiko Agatsuma
Mai Iwaya
Masanori Yasuo
Kazuhisa Urushihata
Toshiki Yokoyama
Masayuki Hanaoka
Tomonobu Koizumi
Source :: Internal medicine (Tokyo, Japan). 50(24)
Publication Year :: 2011
Abstract: A 66-year-old man was diagnosed with autoimmune pancreatitis in February 2009 and started 40 mg of oral prednisolone followed by a maintenance dose of 5 mg daily. The patient developed a cough in October 2010 and visited our division. He had a high serum concentration of immunoglobulin (Ig) G4 and his chest computed tomography showed airway stenosis without bilateral hilar lymphadenopathy (BHL). The bronchial biopsy specimens revealed lymphoplasmacytic infiltrations with IgG4-positive/IgG-positive plasma cells of more than 50%. Thus, we diagnosed the airway lesion with IgG4-related airway involvement. This is the first report of a patient with IgG4-related airway involvement without BHL.<br />Article<br />INTERNAL MEDICINE. 50(24):3023-3026 (2011)

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