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A micromagnetic actuator for biomolecule manipulation

Authors :
Paul Galvin
Marin Gheorghe
Hervé Rostaing
Hichem Chetouani
Laboratoire de Génie Electrique de Grenoble (G2ELab)
Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS)
Tyndall National Institute [Cork]
Garcia, Sylvie
Source :
Sensors and Actuators A: Physical, Sensors and Actuators A: Physical, Elsevier, 2007, 135 (2), pp.776-781
Publication Year :
2007
Publisher :
Elsevier BV, 2007.

Abstract

An efficient and low cost way to attract and mix magnetic beads is reported, in which microserpentines wires shape were used in combination with a permanent magnet to polarize and magnetically saturate beads. The research included the design, modelling and an empirical evaluation of a novel device for manipulation of paramagnetic beads. The results reported indicate that the performance of this device agrees with expectations from the modelling, and suggests that the device has significant potential for applications requiring manipulation of biomolecules within BioMEMS, such isolation and purification of nucleic acids and proteins.

Details

ISSN :
09244247 and 18733069
Volume :
135
Database :
OpenAIRE
Journal :
Sensors and Actuators A: Physical
Accession number :
edsair.doi.dedup.....0295e4f5d83d1e7b97e743c07b701b6d