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The Relationship between the Urinary Cadmium Concentration and Cause-Specific Mortality in Subjects without Severe Renal Damage: A 35-Year Follow-Up Study in a Cadmium-Polluted Area of Japan
- Source :
- International Journal of Environmental Research and Public Health, International Journal of Environmental Research and Public Health; Volume 18; Issue 15; Pages: 7747, International Journal of Environmental Research and Public Health, Vol 18, Iss 7747, p 7747 (2021)
- Publication Year :
- 2021
-
Abstract
- We evaluated the association between urinary cadmium concentration (uCd, μg/g Cr) and risk of cause-specific mortality according to urinary β2-microglobulin (MG) concentration. Participants were 1383 male and 1700 female inhabitants of the Cd-polluted Kakehashi River basin. The uCd and β2-MG were evaluated in a survey in 1981–1982, where those participants were followed-up over 35 years later. Among the participants with a urinary β2-MG < 1000, the hazard ratios (HRs) (95% confidence interval) for mortality were significantly higher in those with a uCd of ≥10.0 compared with
- Subjects :
- Male
medicine.medical_specialty
Health, Toxicology and Mutagenesis
Urinary system
010501 environmental sciences
Kidney
01 natural sciences
Article
renal tubular dysfunction
03 medical and health sciences
Renal tubular dysfunction
Japan
Internal medicine
Cause of Death
cohort study
Medicine
Humans
urinary cadmium
mortality
030304 developmental biology
0105 earth and related environmental sciences
Cause of death
0303 health sciences
business.industry
Hazard ratio
Public Health, Environmental and Occupational Health
Environmental Exposure
medicine.disease
Confidence interval
Pneumonia
Heart failure
Female
business
beta 2-Microglobulin
Cohort study
Cadmium
Follow-Up Studies
Subjects
Details
- ISSN :
- 16604601
- Volume :
- 18
- Issue :
- 15
- Database :
- OpenAIRE
- Journal :
- International journal of environmental research and public health
- Accession number :
- edsair.doi.dedup.....027c76e79bd2aa8693717c14d180b527