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Hantavirus infection in Iranian patients suspected to viral hemorrhagic fever
- Source :
- Journal of Medical Virology. 91:1737-1742
- Publication Year :
- 2019
- Publisher :
- Wiley, 2019.
-
Abstract
- Background Hantaviruses are a group of emerging pathogens causing hemorrhagic fever with renal syndrome and Hantavirus cardiopulmonary syndrome in human. This study was conducted to investigate Hantavirus infection among Iranian viral hemorrhagic fever suspected patients. Methods From April 2014 to June 2016, 113 cases from 25 different provinces of Iran were analyzed for Hantavirus infection by IgM/IgG ELISA and pan-Hantavirus RT-PCR tests. Results Although, viral genome was detected in none of the subjects, IgM and IgG antibodies were detected in 19 and 4 cases, respectively. Differentiation of the anti-Hantavirus antibodies according to virus species by EUROLINE Anti-Hantavirus Profile Kit revealed three Puumala virus IgM positive, one Hantaan virus IgM positive, one Hantaan virus IgM borderline, and two Puumala virus IgG borderline cases. Conclusions This study demonstrates the circulation of Hantaviruses in Iran and calls for further investigations of these life-threatening viruses in the country.
- Subjects :
- Hemorrhagic Fevers, Viral
Hantavirus Infections
animal diseases
viruses
Enzyme-Linked Immunosorbent Assay
Iran
Antibodies, Viral
Viral hemorrhagic fever
03 medical and health sciences
0302 clinical medicine
Virology
Humans
Medicine
030212 general & internal medicine
Igg elisa
Virus classification
Hantaan virus
Hantavirus
biology
business.industry
virus diseases
biology.organism_classification
medicine.disease
respiratory tract diseases
Infectious Diseases
Immunoglobulin M
Immunoglobulin G
biology.protein
030211 gastroenterology & hepatology
Puumala virus
Antibody
business
Hantavirus Infection
Subjects
Details
- ISSN :
- 10969071 and 01466615
- Volume :
- 91
- Database :
- OpenAIRE
- Journal :
- Journal of Medical Virology
- Accession number :
- edsair.doi.dedup.....027919c919248ca4b0c29cc273d3e002