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Stochastic gene expression stabilization as a new therapeutic strategy for cancer
- Source :
- BioEssays, BioEssays, Wiley-VCH Verlag, 2012, 34 (3), pp.170-173. ⟨10.1002/bies.201100149⟩, BioEssays, 2012, 34 (3), pp.170-173. ⟨10.1002/bies.201100149⟩
- Publication Year :
- 2012
- Publisher :
- HAL CCSD, 2012.
-
Abstract
- Current differentiation therapies for cancer may not be effective because it might not be enough to only use molecules targeting chromatin remodelers. It may also be necessary to stabilize the re-expressed genes to convert malignant cells into benign ones.
- Subjects :
- Cell signaling
stochastic gene expression
Cellular differentiation
[SDV]Life Sciences [q-bio]
Cell Communication
ACUTE MYELOID-LEUKEMIA
Biology
Bioinformatics
General Biochemistry, Genetics and Molecular Biology
Epigenesis, Genetic
03 medical and health sciences
0302 clinical medicine
stabilization model of cell differentiation
Differentiation therapy
Neoplasms
Gene expression
medicine
Tumor Microenvironment
Humans
cancer
cellular interactions
Gene
030304 developmental biology
MALIGNANCY
0303 health sciences
Tumor microenvironment
Stochastic Processes
CELL-DIFFERENTIATION
ORIGIN
Cancer
Cell Differentiation
medicine.disease
Chromatin Assembly and Disassembly
3. Good health
Chromatin
TUMOR SUPPRESSION
Gene Expression Regulation, Neoplastic
TRANS-RETINOIC ACID
TISSUE
030220 oncology & carcinogenesis
DIFFERENTIATION THERAPY
Cancer research
Genetic Engineering
STEM-CELLS
Genes, Neoplasm
Subjects
Details
- Language :
- English
- ISSN :
- 02659247 and 15211878
- Database :
- OpenAIRE
- Journal :
- BioEssays, BioEssays, Wiley-VCH Verlag, 2012, 34 (3), pp.170-173. ⟨10.1002/bies.201100149⟩, BioEssays, 2012, 34 (3), pp.170-173. ⟨10.1002/bies.201100149⟩
- Accession number :
- edsair.doi.dedup.....0267bd75b3bb2b0ada8028da5b9dd816