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Virus del herpes humano tipo 6 y tipo 7 en receptores de trasplantes
- Source :
- Enfermedades Infecciosas y Microbiología Clínica. 21:424-432
- Publication Year :
- 2003
- Publisher :
- Elsevier BV, 2003.
-
Abstract
- Recent years have witnessed a growing interest in the role of human herpesvirus (HHV) type 6 and type 7 as emerging pathogens or copathogens in transplant recipients. Both HHV-6 and HHV-7 belong to the beta-herpesvirus family and are closely related to another member of the family, cytomegalovirus. After the primary infection, these viruses remain latent in the human host and can reactivate after transplantation. Various clinical processes such as fever, rash, pneumonitis, encephalitis, hepatitis, and myelosuppression have been described in association with herpesvirus. Moreover, a growing body of evidence suggests that the major impact of HHV-6 and HHV-7 reactivation in transplantation is related to indirect effects, such as their association with cytomegalovirus disease, increased opportunistic infections, and graft dysfunction and rejection. The pathogenesis of HHV-6 and HHV-7 during the post-transplantation period, the methods used for their diagnosis, and the evaluation of antiviral drugs and strategies for their prevention and treatment are now the subject of extensive research.
- Subjects :
- Hepatitis
Microbiology (medical)
medicine.medical_specialty
viruses
medicine.medical_treatment
virus diseases
Cytomegalovirus
Hematopoietic stem cell transplantation
Biology
medicine.disease
medicine.disease_cause
Rash
Virology
Organ transplantation
Transplantation
Immunology
medicine
medicine.symptom
Encephalitis
Pneumonitis
Subjects
Details
- ISSN :
- 15781852 and 0213005X
- Volume :
- 21
- Database :
- OpenAIRE
- Journal :
- Enfermedades Infecciosas y Microbiología Clínica
- Accession number :
- edsair.doi.dedup.....0263f2f3f6f63219091b7339b6e7619e