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Isolation and genomic characterization of gosling gout caused by a novel goose astrovirus
- Source :
- Transboundary and Emerging Diseases. 65:1689-1696
- Publication Year :
- 2018
- Publisher :
- Hindawi Limited, 2018.
-
Abstract
- A severe infectious disease characterized with gout, haemorrhage and swellings of kidneys has affected goslings around the major goose-producing regions in China since November 2016. A Novel goose-origin astrovirus (AStV), designated as AStV/SDPY/Goose/1116/17 (AStV-SDPY) strain, was isolated from diseased goslings, and experimental reproduction of gout was successful using the AStV-SDPY strain. Additionally, the AStV-SDPY was conducted for its full genome sequencing characterization using next-generation sequencing (NGS) technique on Illumina HiSeq platform. A complete genome of the AStV-SDPY was 7,252 nt in length and encoded three viral proteins. Phylogenetic analysis revealed that AStV-SDPY strain belongs to an independent branch of avian astroviruses, and the nucleotide homology among AStV-SDPY and other classic avian astrovirus strains was only 48.8%-68.2%. Results of above data indicated the causative agent of the gosling gout occurring in China is a novel divergent goose astrovirus.
- Subjects :
- 0301 basic medicine
China
medicine.medical_specialty
Gout
040301 veterinary sciences
Genome, Viral
Genome
DNA sequencing
Astrovirus
0403 veterinary science
03 medical and health sciences
Goose
Phylogenetics
Astroviridae Infections
Molecular genetics
biology.animal
Geese
medicine
Animals
Phylogeny
Poultry Diseases
Whole genome sequencing
Base Sequence
General Veterinary
General Immunology and Microbiology
biology
Phylogenetic tree
High-Throughput Nucleotide Sequencing
Genomics
04 agricultural and veterinary sciences
General Medicine
biology.organism_classification
Virology
030104 developmental biology
Astroviridae
Subjects
Details
- ISSN :
- 18651674
- Volume :
- 65
- Database :
- OpenAIRE
- Journal :
- Transboundary and Emerging Diseases
- Accession number :
- edsair.doi.dedup.....0262a7050f85eee8e049ad0f6309228a