Additional file 8: of (Arg)9-SH2 superbinder: a novel promising anticancer therapy to melanoma by blocking phosphotyrosine signaling

Figure S6. The penetration and toxicity effects of (Arg)9-GST SH2 TrM on PBMCs. (a) The level of pY proteins was very low in PBMCs compared with B16F10 cells. (b) (Arg)9-GST-SH2 TrM protein could enter into PBMCs, but could not efficiently be enriched by pY proteins in these non-cancerous cells, thus the green signal was observed to be weak. All images shown are representative of at least three independent experiments. (PPTX 329 kb)