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Antimicrobial activity and active compounds of a Rhus verniciflua Stokes extract
- Source :
- Zeitschrift für Naturforschung C. 73:457-463
- Publication Year :
- 2018
- Publisher :
- Walter de Gruyter GmbH, 2018.
-
Abstract
- The Rhus verniciflua Stokes (RVS) extract is used as a traditional herbal medicine in Southeast Asian countries such as Korea and China. In the present study, one phenolic acid and six flavonoids were isolated from an 80% ethanol RVS extract to examine their antimicrobial activities. These compounds were identified as 3′,4′,7-trihydroxyflavone (1), methyl gallate (2), gallic acid (3), fusti (4), fisetin (5), butin (6), and sulfuretin (7) by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and nuclear magnetic resonance spectroscopy. The antimicrobial activities of compounds 5 and 6 (at a dose of 16 μg/mL each) were superior to that of the control, cycloheximide (at a dose of 25 μg/mL), against Hypocrea nigricans; additionally, the activities of compounds 1 and 2 (at a dose of 8 μg/mL each) were superior to the control against Penicillium oxalicum. Also, chemical compounds 1 and 5 (at a dose of 16 μg/mL each) had higher activities than the control (25 μg/mL) against Trichoderma virens. Chemical compound 1 (at a dose of 8 μg/mL) had a similar activity to that of the control against Bacillus subtilis. The obtained results suggest that the RVS extract could be a promising food and nutraceutical source because of the antimicrobial properties of its phenolic compounds.
- Subjects :
- 0301 basic medicine
Chemical compound
Hypocrea
Rhus
Southeast asian
General Biochemistry, Genetics and Molecular Biology
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Nutraceutical
Anti-Infective Agents
Gallic Acid
Benzopyrans
Gallic acid
Methyl gallate
Benzofurans
Flavonoids
Trichoderma
Traditional medicine
Phenolic acid
Antimicrobial
030104 developmental biology
chemistry
030220 oncology & carcinogenesis
Fisetin
Bacillus subtilis
Drugs, Chinese Herbal
Subjects
Details
- ISSN :
- 18657125 and 09395075
- Volume :
- 73
- Database :
- OpenAIRE
- Journal :
- Zeitschrift für Naturforschung C
- Accession number :
- edsair.doi.dedup.....021edabb56962d4367ccd7a3f4fd6549