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Priorities for future research into asthma diagnostic tools: A PAN-EU consensus exercise from the European asthma research innovation partnership (EARIP)
- Source :
- Clinical & Experimental Allergy, 48(2), 104-120. Wiley-Blackwell Publishing Ltd
- Publication Year :
- 2018
-
Abstract
- The diagnosis of asthma is currently based on clinical history, physical examination and lung function, and to date, there are no accurate objective tests either to confirm the diagnosis or to discriminate between different types of asthma. This consensus exercise reviews the state of the art in asthma diagnosis to identify opportunities for future investment based on the likelihood of their successful development, potential for widespread adoption and their perceived impact on asthma patients. Using a two-stage e-Delphi process and a summarizing workshop, a group of European asthma experts including health professionals, researchers, people with asthma and industry representatives ranked the potential impact of research investment in each technique or tool for asthma diagnosis and monitoring. After a systematic review of the literature, 21 statements were extracted and were subject of the two-stage Delphi process. Eleven statements were scored 3 or more and were further discussed and ranked in a face-to-face workshop. The three most important diagnostic/predictive tools ranked were as follows: “New biological markers of asthma (eg genomics, proteomics and metabolomics) as a tool for diagnosis and/or monitoring,” “Prediction of future asthma in preschool children with reasonable accuracy” and “Tools to measure volatile organic compounds (VOCs) in exhaled breath.”.
- Subjects :
- medicine.medical_specialty
Consensus
Allergy
diagnosis
Immunology
MEDLINE
Delphi method
Physical examination
asthma, children, lung function, inflammation, diagnosis
Diagnostic tools
03 medical and health sciences
0302 clinical medicine
children
medicine
Immunology and Allergy
Humans
Metabolomics
030212 general & internal medicine
Lung function
Asthma
medicine.diagnostic_test
business.industry
Health Priorities
Research
lung function
medicine.disease
Prognosis
respiratory tract diseases
Respiratory Function Tests
Europe
030228 respiratory system
1117 Public Health And Health Services
Breath Tests
inflammation
1107 Immunology
Family medicine
General partnership
Objective test
business
Biomarkers
Subjects
Details
- ISSN :
- 13652222 and 09547894
- Volume :
- 48
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
- Accession number :
- edsair.doi.dedup.....01d1958b8bbda4e170d443c468751ce0