Embryos refrozen-thawed by vitrification lead to live births: Case report

Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:25:28Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:41:41Z : No. of bitstreams: 1 2-s2.0-79960559745.pdf: 340611 bytes, checksum: 48f2338ff315fa19c470805cab404c17 (MD5) Made available in DSpace on 2014-05-27T11:25:28Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-03-01 Objective: To describe two successful cases of utilizing refrozen blastocysts by vitrification derived from supernumerary embryos. Design: Case report. Setting: Private fertility clinic. Subjects: Two infertility couple. Interventions: Refrozen blastocysts by vitrification derived from supernumerary embryos. Main outcome measures: Obstetric and pediatric results. Results: Two pregnancies obtained from refrozen-warmed blastocysts led to two healthy babies being born without clinical or genetic problems. Conclusion: These case reports support the notion of safely repeating cryopreservation. However, despite these favorable results, there is still a need for prospective controlled studies on the obstetric and neonatal repercussions of refreezing and of vitrification in particular. © 2010 Middle East Fertility Society. Center for Human Reproduction Prof. Franco Jr. Ribeirão Preto, Av. Prof. Joã o Fiusa, CEP 14025- 310 Ribeirão Preto, São Paulo Paulista Center for Diagnosis Research and Training, Ribeirão Preto Department of Gynecology and Obstetrics Botucatu Medical School State University - UNESP, São Paulo Department of Obstetrics and Gynecology University of Schleswig-Holstein, Luebeck Department of Gynecology and Obstetrics Botucatu Medical School State University - UNESP, São Paulo