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MBGD update 2013: the microbial genome database for exploring the diversity of microbial world

Authors :
Hiroyo Nishide
Motohiro Mihara
Ikuo Uchiyama
Hirokazu Chiba
Source :
Nucleic Acids Research
Publication Year :
2012
Publisher :
Oxford University Press (OUP), 2012.

Abstract

The microbial genome database for comparative analysis (MBGD, available at http://mbgd.genome.ad.jp/) is a platform for microbial genome comparison based on orthology analysis. As its unique feature, MBGD allows users to conduct orthology analysis among any specified set of organisms; this flexibility allows MBGD to adapt to a variety of microbial genomic study. Reflecting the huge diversity of microbial world, the number of microbial genome projects now becomes several thousands. To efficiently explore the diversity of the entire microbial genomic data, MBGD now provides summary pages for pre-calculated ortholog tables among various taxonomic groups. For some closely related taxa, MBGD also provides the conserved synteny information (core genome alignment) pre-calculated using the CoreAligner program. In addition, efficient incremental updating procedure can create extended ortholog table by adding additional genomes to the default ortholog table generated from the representative set of genomes. Combining with the functionalities of the dynamic orthology calculation of any specified set of organisms, MBGD is an efficient and flexible tool for exploring the microbial genome diversity.

Details

ISSN :
13624962 and 03051048
Volume :
41
Database :
OpenAIRE
Journal :
Nucleic Acids Research
Accession number :
edsair.doi.dedup.....018eec624c130f853a02d52ac826b0a0
Full Text :
https://doi.org/10.1093/nar/gks1006