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Antimicrobial, antioxidant and phytochemical investigation of Balanites aegyptiaca (L.) Del. edible fruit from Sudan
- Source :
- African Journal of Biotechnology; Vol 11, No 52 (2012); 11535-11542
- Publication Year :
- 2012
- Publisher :
- Academic Journals, 2012.
-
Abstract
- The methanol extract of the fruit (edible mesocarp) of Balanites aegyptiaca (L.) Del., a popular plant from Sudan, widely employed in Sudanese folk medicine was screened for antimicrobial, antioxidant and some active phytochemical compounds. The extract showed the presence of saponin, terpenoids, phenolic compounds and alkaloids. The methanolic extract of the fruits extracted from B. aegyptiaca exhibited a strong antioxidant activity in the DPPH assay and a potent capacity in preventing linoleic acid oxidation. Methanol extracts (50 and 100 mg/ml) were tested on several microbial strains using agar-well diffusion, minimum inhibitory concentration (MIC), minimum bacterial concentration (MBC) and minimum fungal concentration (MFC) methods. These experiments were performed on ten bacterial strains (five Gram-positives and five Gram-negatives) and four fungal strains. Methanol extracts, particularly at concentration of 100 mg/ml was found to be active against all bacterial and fungal strains and it was comparable to standard antibiotics Gentamicin and Amphotericin B. These findings support some of the traditional applications of the fruit of B. aegyptiaca against microbial aliments. It is therefore recommended that further studies regarding fractionation, separation and purification of these active antimicrobial compounds are required, in addition to toxicological evaluation in vivo.Key words: Balaneties aegyptiaca, antibacterial, antifungal, phytochemical, antioxidant, methanol extract.
- Subjects :
- chemistry.chemical_classification
Balaneties aegyptiaca, antibacterial, antifungal, phytochemical, antioxidant, methanol extract
Antioxidant
Traditional medicine
DPPH
medicine.medical_treatment
Saponin
Biology
Antimicrobial
Applied Microbiology and Biotechnology
Terpenoid
Minimum inhibitory concentration
chemistry.chemical_compound
chemistry
Phytochemical
Botany
Genetics
medicine
Agronomy and Crop Science
Molecular Biology
Balanites aegyptiaca
Biotechnology
Subjects
Details
- ISSN :
- 16845315
- Volume :
- 11
- Database :
- OpenAIRE
- Journal :
- AFRICAN JOURNAL OF BIOTECHNOLOGY
- Accession number :
- edsair.doi.dedup.....018516b7d1f30f28d320b58489bd727a