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Factors associated with dizygotic twinning after IVF treatment with double embryo transfer
- Source :
- Human Reproduction, 27, 10, pp. 2966-70, Human Reproduction, 27(10), 2966-2970. Oxford University Press, Human Reproduction, 26(supplement 1), I33-I33. Oxford University Press, Human Reproduction, 27, 2966-70, Lambers, M J, Groeneveld, E, Stakelbeek, M E F, van den Belt-Dusebout, A W, de Mooij, Y M, Heijmans, M W, Schats, R, Hompes, P G A, Hoek, A, Burger, C, van Leeuwen, F E & Lambalk, C B 2011, ' Factors associated with dizygotic twinning after IVF treatment with double embryo transfer ', Human Reproduction, vol. 26, no. supplement 1, pp. I33-I33 ., Groeneveld, E, Lambers, M J, Stakelbeek, M E F, Mooij, T M, van den Belt-Dusebout, A W, Heijmans, M W, Schats, R, Hompes, P G A, Hoek, A, Burger, C W, van Leeuwen, F E & Lambalk, C B 2012, ' Factors associated with dizygotic twinning after IVF treatment with double embryo transfer ', Human Reproduction, vol. 27, no. 10, pp. 2966-2970 . https://doi.org/10.1093/humrep/des258
- Publication Year :
- 2012
-
Abstract
- Item does not contain fulltext BACKGROUND: Dizygotic twin pregnancies after IVF treatment are the result of multiple embryos transferred into the uterine cavity, followed by successful double implantation. Factors that increase the chance of multiple implantation after IVF are relatively unknown. The present study aimed to investigate whether features of body composition, such as maternal height, weight and body mass index (BMI) are associated with an increased chance of dizygotic twinning after IVF with double embryo transfer (DET). METHODS: This study was conducted using data from a large Dutch nationwide cohort that comprised 19 861 women who had IVF or ICSI treatment between 1983 and 1995 (OMEGA study). First 'fresh' IVF and ICSI cycles with DET resulting in a delivery of a singleton or twin (living as well as stillborn) were selected. A multivariable logistic regression analysis was performed, with the delivery of a singleton or twin as the dependent variable and height, weight, BMI, maternal age, number of retrieved oocytes, use of alcohol, smoking, highest level of education and parity as independent variables. RESULTS: Of the 6598 women who completed their first IVF or ICSI cycle, 2375 had DET, resulting in 496 deliveries of 371 singletons and 125 twins. Multivariable regression analysis revealed that tall women (>1.74 cm) and women with a high number of retrieved oocytes (>8) had an increased chance of dizygotic twinning [OR: 1.8 (95% CI: 1.0-3.4) and OR: 2.2 (95% CI: 1.3-3.8), respectively]. CONCLUSIONS: Our data demonstrate that tall stature and increased number of retrieved oocytes independently increase the chance of dizygotic twinning after IVF with DET.
- Subjects :
- double embryo transfer (DET)
Logistic regression
Body Mass Index
0302 clinical medicine
HEIGHT
Pregnancy
Risk Factors
Twins, Dizygotic
030212 general & internal medicine
reproductive and urinary physiology
2. Zero hunger
RISK
030219 obstetrics & reproductive medicine
OVARIAN STIMULATION
Obstetrics
Singleton
Rehabilitation
Obstetrics and Gynecology
WOMEN
CANCER
Embryo transfer
female genital diseases and pregnancy complications
Cohort
embryonic structures
Female
Adult
medicine.medical_specialty
Dizygotic twin
Fertilization in Vitro
03 medical and health sciences
SDG 3 - Good Health and Well-being
medicine
PREGNANCIES
Humans
Embryo Implantation
Retrospective Studies
Gynecology
business.industry
Body Weight
dizygotic twin pregnancy
Tall Stature
medicine.disease
Embryo Transfer
Body Height
in vitro fertilization (IVF)
BODY-MASS INDEX
Human Reproduction [NCEBP 12]
Logistic Models
Reproductive Medicine
SINGLETON
Multivariate Analysis
Pregnancy, Twin
business
Body mass index
Subjects
Details
- ISSN :
- 14602350 and 02681161
- Database :
- OpenAIRE
- Journal :
- Human Reproduction, 27, 10, pp. 2966-70, Human Reproduction, 27(10), 2966-2970. Oxford University Press, Human Reproduction, 26(supplement 1), I33-I33. Oxford University Press, Human Reproduction, 27, 2966-70, Lambers, M J, Groeneveld, E, Stakelbeek, M E F, van den Belt-Dusebout, A W, de Mooij, Y M, Heijmans, M W, Schats, R, Hompes, P G A, Hoek, A, Burger, C, van Leeuwen, F E & Lambalk, C B 2011, ' Factors associated with dizygotic twinning after IVF treatment with double embryo transfer ', Human Reproduction, vol. 26, no. supplement 1, pp. I33-I33 ., Groeneveld, E, Lambers, M J, Stakelbeek, M E F, Mooij, T M, van den Belt-Dusebout, A W, Heijmans, M W, Schats, R, Hompes, P G A, Hoek, A, Burger, C W, van Leeuwen, F E & Lambalk, C B 2012, ' Factors associated with dizygotic twinning after IVF treatment with double embryo transfer ', Human Reproduction, vol. 27, no. 10, pp. 2966-2970 . https://doi.org/10.1093/humrep/des258
- Accession number :
- edsair.doi.dedup.....01657bb13e846860640195252e72ad93