Resting energy expenditure and carbohydrate oxidation are higher in elderly patients with COPD: a case control study

Made available in DSpace on 2013-08-28T14:12:11Z (GMT). No. of bitstreams: 1 WOS000311425900001.pdf: 227673 bytes, checksum: 952fc8ef1db3be2a1774018dee870ccc (MD5) Made available in DSpace on 2013-09-30T18:24:07Z (GMT). No. of bitstreams: 2 WOS000311425900001.pdf: 227673 bytes, checksum: 952fc8ef1db3be2a1774018dee870ccc (MD5) WOS000311425900001.pdf.txt: 27540 bytes, checksum: c74c4e5135bd1877b2ff33285b9dd01b (MD5) Previous issue date: 2012-06-06 Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-20T13:37:16Z No. of bitstreams: 2 WOS000311425900001.pdf: 227673 bytes, checksum: 952fc8ef1db3be2a1774018dee870ccc (MD5) WOS000311425900001.pdf.txt: 27540 bytes, checksum: c74c4e5135bd1877b2ff33285b9dd01b (MD5) Made available in DSpace on 2014-05-20T13:37:16Z (GMT). No. of bitstreams: 2 WOS000311425900001.pdf: 227673 bytes, checksum: 952fc8ef1db3be2a1774018dee870ccc (MD5) WOS000311425900001.pdf.txt: 27540 bytes, checksum: c74c4e5135bd1877b2ff33285b9dd01b (MD5) Previous issue date: 2012-06-06 Background: Elderly patients with chronic obstructive pulmonary disease (COPD) usually have a compromised nutritional status which is an independent predictor of morbidity and mortality. To know the Resting Energy Expenditure (REE) and the substrate oxidation measurement is essential to prevent these complications. This study aimed to compare the REE, respiratory quotient (RQ) and body composition between patients with and without COPD.Methods: This case-control study assessed 20 patients with chronic obstructive pulmonary disease attending a pulmonary rehabilitation program. The group of subjects without COPD (control group) consisted of 20 elderly patients attending a university gym, patients of a private service and a public healthy care. Consumption of oxygen (O-2) and carbon dioxide (CO2) was determined by indirect calorimetry and used for calculating the resting energy expenditure and respiratory quotient. Body mass index (BMI) and waist circumference (WC) were also measured. Percentage of body fat (%BF), lean mass (kg) and muscle mass (kg) were determined by bioimpedance. The fat free mass index (FFMI) and muscle mass index (MMI) were then calculated.Results: The COPD group had lower BMI than control (p = 0.02). However, WC, % BF, FFMI and MM-I did not differ between the groups. The COPD group had greater RQ (p = 0.01), REE (p = 0.009) and carbohydrate oxidation (p = 0.002).Conclusions: Elderly patients with COPD had higher REE, RQ and carbohydrate oxidation than controls. São Paulo State Univ UNESP, Dept Pathol, Botucatu, SP, Brazil Univ Metodista Piracicaba UNIMEP, Lins, SP, Brazil São Paulo State Univ UNESP, Ctr Phys & Nutrit Metab CeMENutri, Dept Publ Hlth, Botucatu, SP, Brazil Campinas State Univ UNICAMP, Dept Internal Med, Campinas, SP, Brazil Ctr Univ Catolico Salesiano Auxilium Unisalesiano, Dept Physiotherapy, Lins, SP, Brazil FMB UNESP, Dept Saúde Publ, CeMENutri Fac Med, BR-18618970 Botucatu, SP, Brazil São Paulo State Univ UNESP, Dept Pathol, Botucatu, SP, Brazil São Paulo State Univ UNESP, Ctr Phys & Nutrit Metab CeMENutri, Dept Publ Hlth, Botucatu, SP, Brazil FMB UNESP, Dept Saúde Publ, CeMENutri Fac Med, BR-18618970 Botucatu, SP, Brazil