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Rapid diagnosis of Campylobacter pylori infection by urea test paper
- Source :
- Journal of gastroenterology and hepatology. 5(5)
- Publication Year :
- 1990
-
Abstract
- Antral biopsy specimens from 106 patients were examined by culture, Gram stain and silver stain for Campylobacter pylori. Biopsies were also examined by a urea test paper test (UTPT). Of 106 patients studied C. pylori was detected in 68 (64.2%) by Gram stain, silver stain and culture. The UTPT was positive in 63 (59.4%) specimens. Five had false negative results using the UTPT with no false positive subjects. Thus, UTPT has a sensitivity of 92.6% (63/68) and a specificity of 100%. Of the 63 specimens that were UTPT positive, 45 were positive within 1 min, 58 were positive within 5 min. The remainder became positive between 5 and 15 min. There was a negative correlation between the time required for positive UTPT and the number of C. pylori per pit as seen on silver stained sections (P less than 0.05). UTPT is a rapid and sensitive method for detecting C. pylori in gastric mucosa. This enables early therapy, if indicated, before discharge from hospital. Moreover, the urea test paper method is cheap and easily stored.
- Subjects :
- Adult
Male
Pathology
medicine.medical_specialty
Silver Staining
medicine.disease_cause
Sensitivity and Specificity
law.invention
Helicobacter Infections
Silver stain
chemistry.chemical_compound
law
Biopsy
Gastric mucosa
medicine
Humans
Urea
Reagent Strips
Hepatology
medicine.diagnostic_test
Helicobacter pylori
Staining and Labeling
business.industry
Campylobacter
Gastroenterology
medicine.anatomical_structure
Gram staining
chemistry
Gastric Mucosa
Phenazines
Female
Gentian Violet
Negative correlation
Gastritis
medicine.symptom
business
Subjects
Details
- ISSN :
- 08159319
- Volume :
- 5
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Journal of gastroenterology and hepatology
- Accession number :
- edsair.doi.dedup.....013bcf73a9b52b3d1ec9a5951d1d79bc