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ANALYSIS OF MICROMIXER FOR BLOOD FLOW USING ANSYS

Authors :
Saher Manzoor
Maham Akhlaq
Faheem Qasim
Publication Year :
2022
Publisher :
Zenodo, 2022.

Abstract

ANSYS fluid flow simulation is used to design two inlets, one donating the human blood and other donating the anticoagulant and an outlet with consist of the mixture of both inlet fluids. The results show that the basic parameters can largely affect the passive micromixers resulting in better mixing of the fluid owning the change in their velocity, pressure and temperature profiles.<br />{"references":["[1]\tG. Cai, L. Xue, H. Zhang, and J. Lin, \"A Review on Micromixers,\" Micromachines, vol. 8, p. 274, 2017. [2]\tJ. M. Morrissette, P. S. Mahapatra, A. Ghosh, R. Ganguly, and C. M. Megaridis, \"Rapid, Self-driven Liquid Mixing on Open-Surface Microfluidic Platforms,\" Scientific Reports, vol. 7, p. 1800, 2017/05/11 2017. [3]\tX. Liu and S. Li, \"Fabrication of a Three-Layer PDMS Pneumatic Microfluidic Chip for Micro Liquid Sample Operation,\" SLAS TECHNOLOGY: Translating Life Sciences Innovation, vol. 25, pp. 151-161, 2020/04/01 2019. [4]\tB. Yin, W. Yue, A. S. M. M. F. Sohan, T. Zhou, C. Qian, and X. Wan, \"Micromixer with Fine-Tuned Mathematical Spiral Structures,\" ACS Omega, vol. 6, pp. 30779-30789, 2021/11/16 2021. [5]\tL. Falk and J. M. Commenge, \"Performance comparison of micromixers,\" Chemical Engineering Science, vol. 65, pp. 405-411, 2010/01/01/ 2010. [6]\tJ.-N. Kuo, H.-S. Liao, and X.-M. Li, \"Design optimization of capillary-driven micromixer with square-wave microchannel for blood plasma mixing,\" Microsyst. Technol., vol. 23, pp. 721–730, 2017. [7]\tL. Diéguez, M. Winter, S. Molan, P. Monis, B. King, and B. Thierry, \"Disposable microfluidic micromixers for effective capture of Cryptosporidium parvum oocysts from water samples,\" Journal of Biological Engineering, vol. 12, p. 4, 2018/03/27 2018. [8]\tK. Karthikeyan and L. Sujatha, \"Study of Permissible Flow Rate and Mixing Efficiency of the Micromixer Devices,\" International Journal of Chemical Reactor Engineering, vol. 17, 2019. [9]\tX. Luo, Y. Cheng, W. Zhang, K. Li, P. Wang, and W. Zhao, \"Mixing performance analysis of the novel passive micromixer designed by applying fuzzy grey relational analysis,\" International Journal of Heat and Mass Transfer, vol. 178, p. 121638, 2021/10/01/ 2021. [10]\tN. Tran-Minh, F. Karlsen, T. Dong, and H. Le-The, \"A Simple and Low Cost Micromixer for Laminar Blood Mixing: Design, Optimization, and Analysis,\" in Biomedical Informatics and Technology, Berlin, Heidelberg, 2014, pp. 91-104. [11]\tC. P. Fonte, D. F. Fletcher, P. Guichardon, and J. Aubin, \"Simulation of micromixing in a T-mixer under laminar flow conditions,\" Chemical Engineering Science, vol. 222, p. 115706, 2020/08/31/ 2020. [12]\tJ. J. Hathcock, \"Flow Effects on Coagulation and Thrombosis,\" Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 26, pp. 1729-1737, 2006/08/01 2006. [13]\tP. N. Immanuel, Y.-H. Chiu, and S.-J. Huang, \"Microfluidic Simulation and Optimization of Blood Coagulation Factors and Anticoagulants in Polymethyl Methacrylate Microchannels,\" Coatings, vol. 11, 2021. [14]\tZ. Abdelmalek and M. Y. Abdollahzadeh Jamalabadi, \"Numerical Simulation of Micromixing of Particles and Fluids with Galloping Cylinder,\" Symmetry, vol. 12, 2020. [15]\tM. J. Afzal, M. W. Ashraf, S. Tayyaba, A. H. Jalbani, and F. Javaid, \"Computer Simulation Based Optimization of Aspect Ratio for Micro and Nanochannels,\" Mehran University Research Journal of Engineering and Technology, vol. 39, pp. 779-791, 2020. [16]\tM. J. Afzal, S. Tayyaba, M. W. Ashraf, M. K. Hossain, and N. Afzulpurkar, \"Fluidic simulation and analysis of spiral, U-shape and curvilinear nano channels for biomedical application,\" in 2017 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO), 2017, pp. 190-194. [17]\tM. J. Afzal, S. Tayyaba, M. W. Ashraf, M. K. Hossain, M. J. Uddin, and N. Afzulpurkar, \"Simulation, fabrication and analysis of silver based ascending sinusoidal microchannel (ASMC) for implant of varicose veins,\" Micromachines, vol. 8, p. 278, 2017. [18]\tM. J. Afzal, M. W. Ashraf, S. Tayyaba, M. K. Hossain, and N. Afzulpurkar, \"Sinusoidal Microchannel with Descending Curves for Varicose Veins Implantation,\" Micromachines, vol. 9, p. 59, 2018. [19]\tM. J. Afzal, F. Javaid, S. Tayyaba, M. W. Ashraf, and M. I. Yasin, \"Study of Constricted Blood Vessels through ANSYS Fluent,\" Biologia, vol. 66 (II), pp. 197-201, 2020. [20]\tM. J. Afzal, F. Javaid, S. Tayyaba, M. W. Ashraf, and M. K. Hossain, \"Study on the Induced Voltage in Piezoelectric Smart Material (PZT) Using ANSYS Electric & Fuzzy Logic,\" 2020. [21]\tK. Muhammad Talha, \"STUDY OF THERMAL DEFORMATION ANALYSIS IN AL-STEEL AND CU-STEEL BIMETAL COMPOSITES BY ANSYS STATIC STRUCTURAL \" PJEST, vol. 1, p. 11, 11 May 2021. [22]\tM. J. Afzal, F. Javaid, S. Tayyaba, A. Sabah, and M. W. Ashraf, \"Fluidic simulation for blood flow in five curved Spiral Microchannel,\" Biologia, vol. 65, p. 141, 2019."]}

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....011516cecc23e97dd0be42685a7fa149
Full Text :
https://doi.org/10.5281/zenodo.5851258