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Supplementary Figures S1-S5 from A Cell-Based MAPK Reporter Assay Reveals Synergistic MAPK Pathway Activity Suppression by MAPK Inhibitor Combination in BRAF-Driven Pediatric Low-Grade Glioma Cells

Authors :
Till Milde
Olaf Witt
Tilman Brummer
Marc Remke
David T.W. Jones
Stefan M. Pfister
Cornelis M. van Tilburg
Darren Hargrave
Tobias Rubner
Alexander C. Sommerkamp
Johanna Vollmer
Thomas Hielscher
Jonas Ecker
Stefan Pusch
Jennifer Jansen
David Pauck
Viktoria Marquardt
Florian Selt
Juliane L. Buhl
Romain Sigaud
Diren Usta
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Suppl. Figure S1 shows "Initial MAPKi screen using metabolic activity as readout". Suppl. Figure S2 shows "Western blot validation of MAPK pathway alterations in HEK293T cells". Suppl. Figure S3 shows "Dose-response curves of MAPKi combination treatment in DKFZ-BT66 pDIPZ-CMV cells". Suppl. Figure S4 shows "Dose response curves of MAPKi combination treatment in BT 40 pDIPZ CMV cells". Suppl. Figure S5 shows "Isobolograms of MAPKi combination treatment in DKFZ-BT66 pDIPZ-CMV and BT-40 pDIPZ-CMV cells"

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....010f5ff900ab07314c3c4d69dde7540d