Effects of sleep apnea and kidney dysfunction on objective sleep quality in nondialyzed patients with chronic kidney disease: an ESADA study

Study Objectives: Patients with chronic kidney disease (CKD) often report poor sleep quality, but they commonly exhibit OSA. The aim of this study was to evaluate the influence of OSA severity and of estimated glomerular filtration rate impairment on objective sleep quality in nondialyzed patients with CKD, defined as an estimated glomerular filtration rate
ResMed Foundation ResMed Foundation European Respiratory Society, ERS European Cooperation in Science and Technology, COST
All authors have seen and approved the manuscript. By submitting the manuscript to the journal, the authors affirm that it is an original manuscript, is unpublished work if not as an abstract, and is not under consideration elsewhere. Work for this study was performed at institutions listed in the acknowledgments. This study was funded by support for the European Sleep Apnea Database network from the European Union COST Action B26 and the European Respiratory Society–funded Clinical Research Collaboration (funding 2015–2020). Unrestricted seed grants from the ResMed Foundation and the Philips Respironics Foundation for the establishment of the database in 2007 and 2011 are gratefully acknowledged. The European Sleep Apnea Database has a scientific collaboration with Bayer AG. O.M., F.C, G.R., P.S., P.J., O.K.B., I.B., S.S., A.P., R.S., and J.V. do not have any financial interests or connections, direct or indirect, or other situations that might raise the question of bias in the work reported or the conclusions, implications, or opinions stated. J.H. reports grants from ResMed, Philips Respironics, Bayer, and the European Respiratory Society related to maintenance of the database on behalf of the European Sleep Apnea Database group. L.G. reports a collaboration between the European Sleep Apnea Database network and Bayer. M.R.B. reports research financial support by Vivisol and Medicair Italy and honoraria from ResMed and Bioproject.