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A conserved fold for fimbrial components revealed by the crystal structure of a putative fimbrial assembly protein (BT1062) from Bacteroides thetaiotaomicron at 2.2 Å resolution

Authors :
Gye Won Han
Mark W. Knuth
Natasha Sefcovic
Marc André Elsliger
Tamara Astakhova
Marc C. Deller
Heath E. Klock
Carol L. Farr
Xiaohui Cai
Piotr Kozbial
Adam Godzik
Thomas Clayton
Edward Nigoghossian
Qingping Xu
Ian A. Wilson
Herbert L. Axelrod
Henry J Tien
Constantina Bakolitsa
Christine B Trame
Lian Duan
Dana Weekes
Debanu Das
Daniel McMullan
Amanda Nopakun
Christina Puckett
Keith O. Hodgson
Joanna C Grant
Ron Reyes
Kevin K. Jin
David Marciano
Connie Chen
Jiadong Zhou
Dennis Carlton
Abhinav Kumar
Kyle Ellrott
Lukasz Jaroszewski
Andrew Yeh
Tiffany Wooten
Andrew T. Morse
Polat Abdubek
Michelle Chiu
Henry van den Bedem
Linda Okach
Sanjay Krishna
John Wooley
Ashley M. Deacon
Hsiu-Ju Chiu
Mitchell D. Miller
Anna Grzechnik
Scott A. Lesley
Julie Feuerhelm
Source :
Acta Crystallographica Section F: Structural Biology and Crystallization Communications, Acta crystallographica. Section F, Structural biology and crystallization communications, vol 66, iss Pt 10
Publication Year :
2010
Publisher :
International Union of Crystallography, 2010.

Abstract

The crystal structure of BT1062 from Bacteroides thetaiotaomicron revealed a conserved fold that is widely adopted by fimbrial components.<br />BT1062 from Bacteroides thetaiotaomicron is a homolog of Mfa2 (PGN0288 or PG0179), which is a component of the minor fimbriae in Porphyromonas gingivalis. The crystal structure of BT1062 revealed a conserved fold that is widely adopted by fimbrial components.

Details

Language :
English
ISSN :
17443091
Volume :
66
Issue :
Pt 10
Database :
OpenAIRE
Journal :
Acta Crystallographica Section F: Structural Biology and Crystallization Communications
Accession number :
edsair.doi.dedup.....007ddefbe60d7894f526bbc973ac2fbb