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Efficacy of compound traditional Chinese medicine oil in alleviating regorafenib-induced hand-foot skin reaction

Authors :
Liyan Zhang
Jieyuan Cai
Hong Sun
Lin Shen
Source :
Asia-Pacific Journal of Oncology Nursing. 9:125-129
Publication Year :
2022
Publisher :
Elsevier BV, 2022.

Abstract

Regofinib is a novel, oral, anticancer target which greatly improves survival of patients with colorectal cancer. However, it causes 47%-71% patients occur hand-foot skin reaction (HFSR), which affects the quality of life (QOL) or prognosis of patients. However targeted and effective methods are rare. The study attempted to test the efficacy of the compound traditional Chinese medicine (CTCM) oil in relieving HFSR and improving the QOL.The present study was conducted in 85 patients with metastatic colorectal cancer presenting with HFSR from July 2019 to June 2020. These patients were divided into the control group (The post-intervention HFSR remission rate was significantly higher in the intervention group than in the control group (65.1% vs. 16.7%) (The CTCM oil can effectively alleviate HFSR and improve the QOL of patients using regorafenib.

Subjects

Subjects :
Oncology
Oncology (nursing)

Details

ISSN :
23475625
Volume :
9
Database :
OpenAIRE
Journal :
Asia-Pacific Journal of Oncology Nursing
Accession number :
edsair.doi.dedup.....004790a4209a99fcff46e88bd4abb50e