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Predictive factors for pleural drainage volume after uniportal video-assisted thoracic surgery lobectomy for non-small cell lung cancer: a single-institution retrospective study
- Source :
- World Journal of Surgical Oncology, Vol 18, Iss 1, Pp 1-9 (2020), World Journal of Surgical Oncology
- Publication Year :
- 2020
- Publisher :
- BMC, 2020.
-
Abstract
- Objective To identify the predictive factors associated with pleural drainage volume (PDV) after uniportal video-assisted thoracic surgery (VATS) lobectomy for non-small cell lung cancer (NSCLC). Methods A total of 440 consecutive NSCLC patients who underwent uniportal VATS lobectomy were enrolled in this study between November 2016 and July 2019. Thirty-four parameters, including patients’ clinicopathological characteristics and other potential predictors were collected. Daily drainage volume was summed up as PDV. Univariate analysis and multivariate regression models were fitted to identify independent predictive factors for PDV. Results The median PDV was 840 ml during the median drainage duration of 4 days. A strong correlation was observed between PDV and drainage duration (correlation coefficient = 0.936). On univariate analysis, age, forced expiratory volume in 1 s % predicted (FEV1%), left ventricular ejection fraction (LVEF), operation time, serum total protein (TP), and body mass index (BMI) showed a significant correlation with PDV (P value, < 0.001, < 0.001, 0.003, 0.008, 0.028, and 0.045, respectively). Patients with smoking history (P = 0.030) or who underwent lower lobectomy (P = 0.015) showed significantly increased PDV than never smokers or those who underwent upper or middle lobectomy, respectively. On multivariate regression analysis, older age (P< 0.001), lower FEV1% (P< 0.001), lower LVEF (P = 0.011), lower TP (P = 0.013), and lower lobectomy (P = 0.016) were independent predictors of increased PDV. Conclusions Predictive factors of PDV can be identified. Based on these predictors, patients can be treated with tailored individualized safe chest tube management.
- Subjects :
- medicine.medical_specialty
Lung Neoplasms
genetic structures
medicine.medical_treatment
VATS lobectomy
lcsh:Surgery
Pleural drainage volume
030204 cardiovascular system & hematology
lcsh:RC254-282
Ventricular Function, Left
03 medical and health sciences
0302 clinical medicine
Postoperative Complications
Non-small cell lung cancer
Carcinoma, Non-Small-Cell Lung
medicine
Humans
Uniportal VATS lobectomy
Lung cancer
Pneumonectomy
Aged
Retrospective Studies
Univariate analysis
Ejection fraction
business.industry
Thoracic Surgery, Video-Assisted
Research
Retrospective cohort study
Stroke Volume
lcsh:RD1-811
medicine.disease
Prognosis
lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Surgery
Chest tube
030228 respiratory system
Oncology
Cardiothoracic surgery
Drainage
business
Body mass index
Predictive factors
Subjects
Details
- Language :
- English
- ISSN :
- 14777819
- Volume :
- 18
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- World Journal of Surgical Oncology
- Accession number :
- edsair.doi.dedup.....0046cf4b50f04693b0e9f6ea495b93da