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Neuroprotection by brain-wide conditional deletion of LRRC8A in a mouse MCAO model of stroke

Authors :
Balkaya, Mustafa
Mongin, Alexander
Publication Year :
2022
Publisher :
Open Science Framework, 2022.

Abstract

This registration describes experimental design for one ARM of the study exploring the role of volume regulated anion channel (VRAC) in a mouse model of stroke. In this arm we will test the neuroprotective effects of the brain-wide conditional knockout of Lrrc8a (Nestin-Cre-driven deletion)

Details

Database :
OpenAIRE
Accession number :
edsair.doi...........ffe59e8db161a888c0f46583b9fdfd98
Full Text :
https://doi.org/10.17605/osf.io/3s7ab