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Inhibition of ADAM9 expression induces epithelial phenotypic alterations and sensitizes human prostate cancer cells to radiation and chemotherapy

Authors :
Sajni Josson
Peter A.S. Johnstone
Hiroyuki Kubo
Chia-Ling Hsieh
Cynthia Anderson
Rebecca S. Arnold
Shian Ying Sung
Clayton Yates
Murali Gururajan
Leland W.K. Chung
Source :
The Prostate. 71:232-240
Publication Year :
2011
Publisher :
Wiley, 2011.

Abstract

Introduction Recent studies demonstrated the importance of ADAM9 in prostate cancer relapse upon therapy. In this study, we determined the role of ADAM9 in the therapeutic resistance to radiation and chemotherapy.

Details

ISSN :
02704137
Volume :
71
Database :
OpenAIRE
Journal :
The Prostate
Accession number :
edsair.doi...........ffb341200bcaf9d03889c53f054bf2ac
Full Text :
https://doi.org/10.1002/pros.21237