Acute-Phase Response and Amyloid

The acute phase is described as a series of events that occur in response to infection or tissue injury. Inflammation, as expressed clinically by the classical tetrad of dolor, calor, rubor et tumor represents the local reaction to such insults to tissue integrity, whereas the acute-phase phenomena reflect the systemic response in this recpect [56]. The ultimate goal of the inflammatory and acute-phase responses is to restore and maintain homeostasis by destruction and elimination of causative agents, limination of the extent of injury, removal of damaged tissue constituents, and repair.